Fentanyl Metabolism and excretion It interacts with opiate receptors decreasing pain impulse transmission at the spinal cord level and higher in the CNS. Fentanyl is a potent µ-opiate receptor agonist. Also causes peripheral vasodilation increasing venous capacitance and decreases ...Read on
A Place for Board Certified and Board Eligible Pain Management Anesthesiologists to share concerns and important topics relevant to the Practice of Pain.
Propofol Metabolism and excretion Propofol is highly protein-bound in vivo and is metabolised by conjugation in the liver. (1) The half life of elimination of propofol has been estimated at between 2 and 24 hours. Its duration of clinical effect is much shorter, because propofol...Read on